Arizona Republic from Phoenix, Arizona on November 4, 1969 · Page 23
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November 4, 1969

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Arizona Republic from Phoenix, Arizona · Page 23

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Phoenix, Arizona
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Tuesday, November 4, 1969
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Page 23
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Page 23 article text (OCR)

LSD doesn't significantly change chromosomes^ researchers claim Phoenix. Tues., Nov. 4, The Arf/ona Republic 11 Associated Press CHICAGO — Three researchers reported yesterday that in contrast to previous studies they have found that the use of LSD does not cause significant changes in the users' chromosomes. LSD is the popular abbreviation for lysergic acid die- thylamide, an halucinogenic drug which has had widespread illicit use. There has been concern among doctors and others over the possible damage to chromosomes, the carriers of genes which affect heredity. The offspring of LSD users might be born with physical or mental defects, they feared. The researchers said the results' of their studies "would seem to sustain the conclusion that at this time there is no definitive evidence Cat leukemia virus spurs cancer study Associated Press Scientists sought to evaluate yesterday the announcement by a British research team that a virus that causes leukemia in cats has been made to grow in human cell tissues. "This is one of the biggest breakthroughs in cancer research in 20 years," declared Dr. Robert Williamson of the Royal Beatson Hospital in Glasgow, Scotland. "Having this virus isolated means that finding a cure is now a matter of hard slogging." However, William Jarrett, a professor of veterinary pathology and head of the Glasgow University research team that announced the discovery, cautioned: "Don't get too excited about the possibility of a cure being found quickly. But the outlook looks promising." The findings of Jarrett's team first were announced in September at an international symposium in Cherry Hill, N.J. "This is the first natural cancer virus to be discovered," Jarrett said in Glasgow. "It is the first virus ever shown to, cross the species barrier. It will infect any human cell" Dr. Oswald Jarrett, the professor's brother and a member of the research team, said the feline leukemia virus was injected into human cell tissues in the laboratory. "Although it grew well," he said, "it does not follow that the same would happen in a living person." Al Davis, science editor of the American Cancer Society, said the British scientists were "exaggerating a little bit in terms of its real significance." He said the word "cure" should not have been linked with the announcement. In Houston, Dr. Leon Dmochowski, chairman of the department of virology at the University of Texas and a member of the advisory committee of the Leukemia Society of America, said the Glas- go\f finding was "hardly a great breakthrough," but would "serve as a stimulus" to leukemia research. that LSD damages chromosomes of human white blood cells." However, they added, "Further research in this complex field is obviously needed." The researchers are Joe- Hin Tjio, Ph.D., of the National Institute of Arthritis and Metabolic Disease, Bethesda, Md.; Walter N. Pahnke, M.D. and Ph.D., of the Johns Hopkins University school of medicine, Baltimore, and Albert A. Kurland, M.D., of the Maryland Psychiatric Research Center, Baltimore. Their research was conducted with a grant from the National Institute of Mental Health. They reported their findings in the Nov. 3 issue of the Journal of the American Medical Association. They said one major shortcoming "uniformly characterizing" some previous studies is the absence of adequate control measures. "Most important, the chromosomal aberration rate prior to the alleged taking of LSD was not assessed," they said. "With the goal of providing a more definite answer, we undertook a larger prospective study," they added. They used for the study 32 patients scheduled to receive LSD as part of tfceir psychiatric treatment at the Spring Grove State Hospital, Baltimore. The patients were hospitalized for alcoholism or neurotic problems and had never previously taken LSD. They volunteered to be subjects in a study of the potential of LSD in psychiatric treatment. The subjects ranged in age from 20 to 56 years and included five females and 27 males. The subjects were broken into high-dose and low-dose groups. Their statistical analysis, the researchers said, "revealed no significant difference between the before and after LSD chromosomal ab- beration rates for either the high or low dose groups whether analyzed separately or as one group." "Our findings are in contrast to the four studies which have reported more chromosomal abberations in LSD takers than in normal controls," the researchers wrote. They said other research failed to take into account chromosomal abberration before the use of LSD, impurities present hi homemade LSD, and other factors, the report said. IT'S OUR Y/e are celebrating our Tenth Anniversary with spectacular values and presentation of the best in Fad TOWERPIAZA SHOP AT THE BIGGEST-LITTLE STORE IN TOWN for unusual Wall Decor, At- cessorios and all home furnishings . • • plus old fashiontd courtesy and service. Trade-ins welcome Terms to Please! FURNITURE CO. 500 E. Dunlap Open Daily 9 to » • Sat, 9 to t Sun. J to 5 • M4-3351 ICE PALACE A Family Sport! 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