The Nutley Sun from Nutley, New Jersey • A10

10 The Nutley Sun Thursday, June 27, 2002 Roche expands commitment to innovative advanced medicines Roche and Genmab AS (CSE: GEN and Neuer Markt: GE9D) has announced a broad expansion of their current collaboration for the creation and development of human antibody therapeutic products for life-threatening and debilitating diseases. Hoffmann-La Roche Inc. (Roche), based in Nutley, is the U.S. prescription drug unit of the Roche Group, a leading research-based health care enterprise that ranks among the world's leaders in pharmaceuticals, diagnostics and vitamins. As part of the expanded collaboration, Roche is also making an equity investment totaling $20 million at a price of DKK 180 per share.

This expanded program involves a number of new disease targets from Roche; and Genmab expects to initiate approximately 15 new projects in the coming year across a number of therapeutic areas. The program is coordinated by Roche's Pharmaceutical Research and will expand the company's significant commitment to the development of biologicals as innovative new medicines. Under the current agreement Roche has access to Genmab's antibody development capabilities as well as its pre-clinical and clinical development capabilities and Genmab will receive milestones as well as royalty payments on successful products. In certain circumstances Genmab could obtain rights to develop products based on disease targets identified by Roche. If all goals are reached, the value of the collaboration could be as high as $100 million.

"Our alliance with Chamber of Commerce email: nutleychamberaol.com www.nutleychamber.com Open 7 Days! Bni3 Bi-State Shopping Plaza Genmab has the potential to significantly strengthen our position in this important field. We are pleased to further expand our global programs to create and develop important new antibody medicines with Genmab as an important partner," said Jonathan Knowles, head of Roche's Global "The expansion of our existing program underlines the strength of our organization and expertise we can provide for such a valuable partner as Roche," said Lisa N. Drakeman, Ph.D. chief executive officer of Genmab. "We look forward to continuing to work together with Roche in order to strengthen Genmab's broad portfolio of products in development." Genmab AS is a biotechnology company that creates and develops fully human antibodies for the treatment of life-threatening and debilitating diseases.

Genmab has numerous products in development to treat cancer, rheumatoid arthritis and other inflammatory conditions, and intends to assemble a broad portfolio of new therapeutic products arising from research into the human genome. At present, Genmab's commercial opportunities are based upon research conducted at leading inter- "7 UPPIES 0ld TaPPan- NJ Summer is the "FURPICT" time to add a furry member to your family! I Largest selection of top quality puppies from private breeders. Free Veternary Visit Free Micro Chipping Free Vaccination Free Double your Money Back Health Guarantee national companies, including Roche, Immunex Corporation, Oxford Glyco-Sciences Medarex, deCODE Genetics, Scancell, Sequenom, Eos Biotechnology Glaucus Proteomics B.V., Bionomics, Paradigm Therapeutics and ACE Bio-Sciences, as well as in its own laboratories. A broad alliance provides Genmab with access to Medarex array of proprietary technologies, including the UltiMAb(TM) platform for the rapid creation and development of fully human antibodies to virtually any disease target. Genmab is headquartered in Denmark and has operations in Utrecht, The Netherlands and Princeton.

For more information about Genmab, visit http genmab. com. Roche discovers, develops, manufactures and markets numerous important prescription drugs that enhance people's health, well-being and quality of life. Among the company's areas of therapeutic interest are: dermatology; genitourinary disease; infectious diseases, including influenza; inflammation, including arthritis and osteoporosis; metabolic diseases, including obesity and diabetes; neurology; oncology; transplantation; vascular diseases; and virology, including HIVAIDS and hepatitis C. For more information on the Roche pharmaceuticals business in the United States, visit the company's website at: Lowest Guarantee! Prices on all your Flea Tick needs: Advantage, Capstar, Frontline Plus, Program, Zoaiac ana 20 Off all outdoor toys (tennis and woter toys included!) 25 Off dll life preservers 20 Off dll tie outs, stokes dnd trolley runs $100 Off ony reguldr priced Puppy or Money CAN Buy You CHAMBER ON SUMMER SCHEDULE Our office will remain open Monday through Thursday and will be closed on Fridays during the months of July and August.

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(Sept. 15 and 22 are matinees.) The cast requires two men and two women in their late 30s to early 40s. Also needed are a woman in her late 20s and two young women who can play age 16. Teenagers are also encouraged to audition for those roles. Actors should be prepared to read from the script at auditions.

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