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the Boston lok Wednesday, November 13, 2013 Panel recommends far wider use of cholesterol drugs Tribe says it will open small casino on Vineyard Percentage of people who would be considered high-risk and be treated with statins: Men in their 50s White 50 Black 60 Women in their 60s White 33 Black 66 Adults, 70 to 75 Men 100 Women 70 NOTE: Numbers pertain only to adults who do not have diabetes. SOURCES: Dr. Roger Blumenthal, Johns Hopkins Hospital globe staff By Deborah Kotz GLOBE STAFF The number of Americans taking cholesterol-lowering statin drugs to prevent cardiovascular disease could double under treatment recommendations issued Tuesday to an estimated 72 million people, or about 30 percent of US adults. The long-awaited update to the cholesterol treatment guideline lowers the threshold for those deemed to be at significant risk for having a heart attack or stroke and encourages doctors to treat these patients with statins even if their cholesterol levels are not elevated. "When you look at the toll that heart disease and stroke deaths take in this country, we probably need to treat more people with statin drugs," said Dr.

Neil Stone, a professor at Northwestern University Fein-berg School of Medicine and chairman of the expert panel that wrote the recommenda- DAVID L. RYANGLOBE STAFF The Wampanoag Tribe of Aquinnah plans to convert an unfinished community center (right) into a gambling hall. Menino to help start urban institute at BU Cites a federal opinion on legality; state insists Aquinnah gave up right tions. More than 700,000 Americans die every year from cardiovascular diseases, but studies have shown that patients who take statins are, as a group, able to reduce their risk of having a heart attack, stroke, STATINS, Page A8 ideas as they tackle urban issues. The center might offer boot camps for city officials, act as a clearinghouse where municipalities could compare data, and serve as a think tank for urban problem solving.

"We want to be the place people go when it comes to urban issues," Menino said Tuesday in an interview at BU. "We're starting now, but in a few years we want to be the leading university when it comes to urban America." Menino will be codirector of the initiative with Graham Wilson, chairman of BU's political science department. MENINO, Page AlO 'It's going to be modest because that's who we are, and we want it to be complementary to the CHERYL ANDREWS-M ALTAI chairwoman, Wampanoag Tribe of Aquinnah lacks the right to build a casino on the island, a world-renowned summer resort. But in a new legal analysis, which the tribe released Tuesday, federal officials said in October that the tribe did not give up rights to develop a casino on its Vineyard land, as the state has long contended. Around the island Tuesday, residents offered mixed opinions about the prospect of a gambling hall hitting their sleepy community.

Some looked forward to the possible economic benefits and antici-CASINO, Page A9 5 -year contract for retiring mayor By Andrew Ryan and Marcella Bombardieri GLOBE STAFF Mayor Thomas M. Menino will trade City Hall for the halls of academia at Boston University, where administrators hope to meld the mayor's pragmatism as an "urban mechanic" with the scholarly muscle of a major university. Menino has been hired to help launch a new Institute on Cities, where mayors and municipal managers from across the globe can share Vast project revived in Westwood Business-residential development, long stalled, signals a Mass. upturn tna By Mark Arsenault GLOBE STAFF The Wampanoag Tribe of Aquinnah announced Tuesday that it intends within months to open the state's first casino, on tribal land on Martha's Vineyard, delivering another shock to an emerging Massachusetts casino industry that has become wildly unpredictable of late. Governor Deval Patrick signaled last evening that he would try to block the tribe's gambling plans, holding to a longstanding position by state officials that the island tribe By Casey Ross GLOBE STAFF After years of delays, one of the state's largest development projects is getting started Wednesday in the town of West-wood, where contractors will begin to build a miniature city with hundreds of new homes, stores, and offices.

The 130-acre University Station project promises to transform a vast stretch of former industrial property along Interstate 95 into a new destination with a Wegmans supermarket and popular retailers such as Nordstrom Rack. The project stalled in 2010 during an economic downturn that dried up funding for large-scale real estate development. Its resurrection by a new team of investors is symbolic of a resurgent economy and housing market in Massachusetts that are fueling a burst of construction activity statewide. "This is a great opportunity WESTWOOD, Page AlO Former Red Sox skipper Terry Francona of the Indians was named American League Manager of the Year, ahead of Boston's World Series-winning John Farrell. CI.

Domestic workers testified of harsh treatment during a State House hearing on a bill to expand legal protections. B7. The US government was given a Jan. 31 deadline to decide whether to seek the death penalty for Dzokhar Tsarnaev in the Marathon bombings case. Bl.

Islanders ponder Views were mixed on whether the Vineyard is the best place for the state's first casino, bi. US nears new curbs on drug makers Spurred by state's compounding pharmacy crisis By Noah Bierman GLOBE STAFF WASHINGTON The Senate cleared a key hurdle Tuesday for a bill intended to reduce the chance of another public health tragedy like last year's shipment of contaminated drugs by a Massachusetts pharmacy, which caused an outbreak of fungal meningitis that killed 64 people. The measure to increase oversight of compounding pharmacies which operate like drug manufacturers but have been regulated loosely is expected to reach President Obama's desk this week, once the Senate takes a final vote. The legislation is the official response to a year of grieving, confusion, and anger, after hundreds of people in 23 states who received steroid injections for back and joint pain came down with mysterious maladies. In addition to the deaths, 751 people were infected.

Others continue to experience debilitating symptoms, including fatigue, rashes, and headaches. Doctors and public health sleuths eventually traced the origin of their suffering to a phar- COMPOUNDING, Page All One World Trade Center with spire 1,776 ft. Antennas are not taken into consideration to determine the height of the Willis Tower, unlike the World Trade Center spire. Willis Tower Chicago 1,451 ft. 1,368 ft.

World Trade Center Building John Hancock Tower 790 ft. 600 ft. 400 ft. 200 ft. Oft.

SOURCE: World Trade Center, AP NEW YORK REGAINS HIGHEST HONORS The Council on Tall Buildings and Urban Habitat has deemed One World Trade Center in lower Manhattan the nation's tallest building, a distinction that long rested with Chicago's Willis Tower. A determination that the 408-foot mast atop the New York building is a spire rather than a mere antenna made the difference. A8. 0 ass' Air apparent Wednesday: Cold, windy; high 38-43, low 30-35. Thursday: Sunny, warmer; high 48-53, low 33-38.

High tide: 7:23 a.m., 7:52 p.m. Sunrise: 6:32 Sunset: 4:24 Complete report, B15 Superimposed on a map of downtown Boston, the development would stretch from the Common to the North End. btation KX'i-' The Obama administration struggled for a way to let people keep their coverage without upending the new health law. Former president Bill Clinton joined the call to let old plans stay in effect next year. A2.

VOL. 284, NO. 136 Suggested retail price $1.25 $2.00 outside of Metro Boston 45319 0 "947 72 5'" 4' i i I 7 HaM Boston Common US Coast fSiiarrl station Shape of University Station development Faneuil Hall 500 FEET A global aid effort gathered momentum in the Philippines, but officials could not say when basic needs would be met. A3. China promised unspecified economic reforms, including a bigger role for the market.

A5. A court declared Egypt's state of emergency over, but a wary military delayed implementation of the ruling. A7. For breaking news, updated stories, and more, visit our website: BostonGlobe.com Nrth.