Press and Sun-Bulletin from Binghamton, New York on September 11, 1963 · 10
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Press and Sun-Bulletin from Binghamton, New York · 10

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Binghamton, New York
Issue Date:
Wednesday, September 11, 1963
Page:
10
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10 PRESS, Binghamton, N. Y. Wed., Sept. 11, 1963 V. S. Government Convinced Judgment on Drug Is Correct trogram for creatine. by Ruth Kessler, a University I posed to krebiozen all along, they called in a group of dis of Pennsylvania student who has By WILLIAM McGAFFIN Special Press Correspondent Washington Government of Its identity as creatine was produced of a chemical com-i pound a little like the electrocardiogram that registers a heart beat on paper. Krebiozen Editorial Cited also confirmed by X-ray dif Trip to Mars In 80s Studied fraction and crystallography worked for the FDA during the summer. By a process of quick elimination, she soon found she was ficials here clearly are convinced that a scientifically-doc GOVERNMENT scientists tinguished scientists from outside the government as insurance that the investigation would be fair and impartial. Three different teams were organized, representing three different scientific approaches. knew even before they opened umented case has been established against krebiozen. Denver cw A five-man ex studies. Finally, mass spectrographs studies conducted at the Massachusetts Institute of Technology established that the krebio- Chicago sponsors of the con pedition to Mars sometime in the 1980s is under study. troversial alleged cancer drug cried foul after the officials LUot C. Payson, chief of ad On each team, the government raen sample was either crea Special Press Correspondence down to 200 or 300 spectrograms. EACH OF THESE' was matched against the krebiozen spectrogram. Progressing alphabetically, she was in the "c" section of the "picture book" when she came on the spectrogram for creatine. It matched vanced design for the Martin- declared that an investigation scientists were balanced by an "outside" scientist. had shown krebiozen actually the July 12 sample of krebiozen what its infra-red spectrogram looked like. They had one that Dr. Durovic himself had submitted in September, 1961. They had another identical to it that they had produced from samples of krebiozen he had handed in at that time. What they needed to know was whether this krebiozen Chicago The American Medical Association has cited the Chicago Daily News for a major role in the krebiozen tine, or the substance it turns into when treated with hydrochloric acid creatinine. The officials have concluded Marietta Corp., said the trip to Mars would take 269 days. The space crew would remain there 455 days before returning. is a common laboratory chemical called creatine, which THERE WAS, for example, controversy. Oliver Field, has proved ineffective against Dr. Raymond Castle of the University of New Mexico; Dr. tions through their physicians, director of the A M A Bureau cancers in animals. But the officials backed up some paying hundreds of dollars in 'contributions' at $9.50 William Bradley of the University of Texas: Dr. Klaus Bie- ' of Investiga their damaging announcement an ampule. mann of the Massachusetts In spectrogram matched any of tion said. with a wealth of detail on the "This potential actually runs the spectrogram for krebiozen, according to officials. Success! The second step the government took was to get some creatine in pure form from chemical supply houses and conduct a series of scientific examinations. Finally, they were ready to scientific detective work that the spectrograms of known chemical compounds. Twenty thousand of ' these have been stitute of Technology; and Dr. Ellis R. Lippincott of the University of Maryland. "Medicine is indebted to the into millions of dollars and yet the books are as much a mys with the assertion that "all these tests leave no doubt" that krebiozen actually is creatine. Dr. Fuess Dies Brookline, Mass. IT) Dr. Claude M. Fuess, 78, retired headmaster of Phillips Academy at Andover, Mass., died Monday night Dr. Fuess served as headmaster from 1933 to made it possible. MEANTIME Senator Paul H. PRIVATE PIANO INSTRUCTION DAM BUCKLEY AT WEEKS & DICKINSON RA 4-2481 or RA S-9139 tery as the substance itself. "pictured." Many more thou Each team was given a sam fy Chicago Daily f News for a ma- ple of the krebiozen powder. All of them reported that they open the vial containing the Chi Douglas (Dem., 111.) who has conducted a long battle to get a government test of krebiozen ' 'A "Questioning Dr. Durovic or his associate, Dr. Andrew Ivy, is like trying to tie water into a bundle, but it seems to us that nor assist m S calling a spade sands have not. Could it be one of the known spectrograms.? The hunt was directed by Mrs. Alma Hayden of the FDA and was actually carried out came up with the same answer. An infra-red spectrogram was cago sample of krebiozen. Obviously aware of charges that the government has been op this situation has gone on long a spade in the irebiozen mater and letting 1948. j made and it matched the spec said that he did not wish to make any comment at this time. enough without some solid an swers. . . . he Senator, (II- Is there any possibility that "The history of krebiozen is OPEN MONDAY and THURSDAY 9:45 to 9:00 OTHER DAYS 9:45 TO 5:15 DIAL RA 2-1231 the sample of krebiozen ana mois Democrat Paul Douglas) as fantastic as any ever entered lyzed here is not the same ma among the colorful stories of terial as that submitted by Dr Sun. douglas know he has someone besides the AMA to deal with now." Steven Durovic and Dr. Andrew medical marvels in this conn try. There are many testima C. Ivy to a Food and Drug Field said "the Chicago Daily nials from satisfied customers, Administration inspector in Chi but these are customary in this cago on July 12th? field. Krebiozen has been dis News "must be given credit as the crystallizing force which has given a government agency None whatever according to tinguished by the protection of FDA Commissioner George P courage, despite the U. S. Sen I some eminent figures m political and other fields." ator who, for reasons best Larrick. He said that a protective system" worked out known to himself insists on keeping krebiozen in the public over the years was followed to THE EDITORIAL concluded: make certain that the sample "The Federal Government eye." submitted "did not lose its iden has restricted the area of krebi-ozen's operation, but in view of tity." ' THE BEGINNING of the end for krebiozen crystallized in an He indicated that the govern' the cloudy record and the po TO EACH HIS OWN! editorial conference in the Chi ment can prove that the sample opened for the first time last cago Daily News offices in mid' July. tentially vast sums of money involved, some appropriate agency of the state ought to step in for the protection of the Tuesday in the presence of government and civilian scientists is the same as the Editors reviewed the bizarre krebiozen history and the star-.tling bits of information that be SHOPPING CENTER OF THE SOUTHERN TIER Conditio public." one handed over in Chicago. WHAT ARE THE chances The editorial gave immediate assurance to the Department of Health, Education and Welfare that the Chicago Daily News gan to emerge from the u. s. Food and Drug Administra then that the scientists may tion's scrutiny of the mysteri have made a mistake in their would support moves aimed at analyses? overcoming congressional bar The official answer to this is that once the scientists deter riers that were being errected It also prompted the Illinois mined that krebiozen actually sstxgisttt State Medical Society and the State of Illinois to launch an in was only cretine they checked and rechecked their conclusion vestigation of krebiozen. in various ways and always ous agent. Convinced the drug was not only worthless as a cancer treatment but also draining funds from persons unable to afford them, the editors determined their newspaper could no longer allow the controversy to run its customary vacillating course. The review showed the 12-year history to be replete with obstructionist tactics. Over the years, Chicago Daily News edi "When the editorial ap came up with the same an swer. peared, the state medical so ciety said, "our board of trus "It was like looking for a G-E PERSONAL 11' PORTABLE T-V . . . FOR VHF . . . AND . . . UHF tees voted to recommend to needle in a haystack," Dr ! Gov. (Otto) Kerner that action Frank H. Wiley. be taken." The big breakthrough in the The probe was urged in a hunt was achieved through the letter to Dr. Franklin Yoder use of infra-red spectrograms director of the State Public torials had continually chided Dr. A. C. Ivy and Dr. Steven Durovic for bypassing accepted said the director of the FDA's Health Department. pharmaceutical chemistry divi sion. WITHIN 24 HOURS, Gover This is a process by wjiich scientific protocol. A NEW THREAT was developing that would only prolong the use of a worthless agent. a wavy-lined "picture" can be cago Daily News learned that Senator Douglas, after persis a closed meeting of National Cancer Institute scientists and the 22 invited cancer experts had found in their final analysis of the cases that krebiozen was of no clinical benefit against cancer. Publication was withheld pending a wrapup of the entire krebiozen investigation, includ ing the actual chemistry of kre biozen s composition. ll-incri screen has daylight blue picture for brightness dyna-power front mounted speaker for rich, realistic sound k built-in adutable antenna lifetime circuit board guarantee the "made in U. S. A." portable you've been waiting for Lawrence S. Fanning, execu tive editor, ordered a 2,000 FEATHERWEIGHT! . . . you'll take it with you every-where you go, it's so easy to carry. Even the children can take it upstairs or down without trouble. nor Kerner named a nine man committee composed chiefly of deans and faculty members of the Chicago medical schools. When Senator Douglas sought, in a telephone call to Kerner, to delay the investigation, the Chicago Daily News, in a July 30 editorial written by Kennedy McArdle, rebuked the senator, advising him to keep hands off a medical matter. Referring to Douglas' contention that the question of kre-biozen's efficacy "should be decided in the laboratory and in the hospitals and not by the medical politicians setting high up in the quarters of the American Medical Association." The editorial commented: "The members and officers of the AMA are trained medical scientists, after all. And we wonder how Douglas could have kept a straight face when he called them politicians." IN EARLY August, the Chicago Daliy News had learned that a preliminary analysis of some of the 508 cases collected by the Food and Drug Administration showed krebiozen to be worthless. word synopsis of the krebipzen history to be published as a tently badgering the National Cancer Institute and the Food and Drug Administration, in Ivy's behalf, introduced a resolution that would compel a government-sponsored test of krebiozen, an unprecedented action in medical annals. A dozen congressmen had endorsed the resolution and cern was evident at the Department of Health, Education and Welfare that it would be adopted. Other support, too, was building up in the nation. The editors concluded it was time to move decisively with an editorial that would sharply focus the krebiozen issue in the strongest possible language. With the approval of Marshall Field, editor and publisher of the Chicago Daily News, an editorial appeared entitled "Krebiozen Is Big Money." WRITTEN BY John M. Johnston, associate editor, who has followed the krebiozen story from its inception, the editorial said in part: "Many thousands of patients have received krebiozen injec background for the events which were to come later. (The Sunday Press ran the synopsis Sept. 8.) DIETING? New tablet helps you stop overeating ...lose pounds and inches while yo enjoy 3 nutritious meals every day. RESISCAL is so effective, it enables you to start losing weight the very first day. No starvation or fad diets. Complete satisfaction guaranteed or money back from manufacturer. Get RESISCAL todoyl Safe, effective. At druggists so light a child can carry it upstairs without harm so inexpensive every member can have his own set so clear that the whole qang can 'enjoy it In early Deptember, the Chi- yhitiSS ' It REMEMBER! LIFETIME GUARANTEE CIRCUIT BOARD .V.V.V. -...a V.V.'NU.' V V. OOk'W.'.. 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